This drug poses an increased hazard of compromised capability to take care of hypertension resulting from peripheral vasodilation along with other mechanisms Label. Outcomes on Serious cancer agony and other sorts of ache
Applying Liquor or tobacco with particular medicines could also trigger interactions to come about. The following interactions are actually selected on The idea in their prospective significance and they are not always all-inclusive.
Although significantly less widespread, quite possibly the most really serious Unintended effects of promethazine/phenylephrine/codeine are described under, together with what to do should they transpire.
We will carry on to watch this protection concern. We are considering added regulatory motion for that OTC codeine products that are available in a few states. OTC codeine products and solutions are available in mix with other medicines for cough and chilly signs or symptoms.
Reduce Seizure Threshold – Promethazine may decreased seizure threshold. It ought to be employed with caution in folks with seizure Conditions or in folks who're using concomitant drugs, which include narcotics or community anesthetics, which can also have an impact on seizure threshold.
If a baby has taken codeine or tramadol and you detect any signs of sluggish or shallow breathing, difficult or noisy breathing, confusion, or unusual sleepiness in a youngster of any age, request professional medical awareness instantly by taking the child to an emergency home or contacting 911.
The most common Unintended effects of promethazine/phenylephrine/codeine are listed below. Inform your healthcare company When you have any of these Negative effects that hassle you.
The Persistent usage of opioids, such as codeine sulfate, might produce obstructive bowel condition, notably in patients with fundamental Ailments of intestinal motility Label. Effects to the central nervous procedure
The chance for severe respiratory problems is greater when You begin this medication and following a dose raise, or if you take the incorrect dose/energy. Getting this medication with alcohol or other medications that can result in drowsiness or breathing difficulties could trigger very major Unwanted effects, which include death. Also, other prescription drugs can influence the removal of codeine out of your overall body, which can affect how codeine will work.
The presence of other health care troubles may well have an affect on the usage of this medicine. Be sure read more you tell your medical doctor Should you have almost every other clinical problems, Specially:
Heart Disease. Promethazine/phenylephrine/codeine should not be utilised In case you have a coronary heart ailment known as coronary artery disease (CAD). Promethazine/phenylephrine/codeine may make this condition even worse.
Narcotic analgesics lead to histamine release, which seems to get chargeable for wheals or urticaria sometimes seen at the site of injection on parenteral administration.
This might not be a complete list of medicines that will communicate with promethazine/phenylephrine/codeine. Usually Check out using your healthcare provider.
On the other hand, In case your mouth carries on to experience dry for more than two weeks, check with your professional medical health care provider or dentist. Continuing dryness on the mouth may enhance the probability of dental illness, together with tooth decay, gum condition, and fungus bacterial infections.